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[Dayo]

I don't know if that will work (see http://wiki.nginx.org/IfIsEvil)

This will almost certainly work:

[code]
location / {
		set_by_lua $backend_ip '
			if ngx.var.cookie_memberid ~= "" and ngx.var.cookie_memberid ~= nil
then
				return "10.10.10.10"
			elseif ngx.var.cookie_clientid ~= "" and ngx.var.cookie_clientid ~=
nil then
				return "10.10.10.15"
			else
				return "10.10.10.20"
			end
		';
		proxy_pass http://$backend_ip;
}
[/code]

Needs 3rd party lua module. 

I only just discovered it myself and starting to learn lua. Seems worth
it as it opens up a lot of possibilities without getting into the if is
evil issues.

Posted at Nginx Forum: http://forum.nginx.org/read.php?2,170775,176154#msg-176154