Uneven High Load on the Nginx Server

[anish10dec]

On some of the Severs Waiting is increasing in uneven way like if we have 3
Set of Servers on all of them Active Connections is around 6K and Writing on
two of the Server its around 500 -600 while on third ts 3000 . On this
server response time is increasing in delivering the content.
This happens even if the content is served from cache of nginx.
Is any parameter in Nginx causing this, as on stopping the Nginx , the same
behaviour shifts to Other Two of them.

This is the Nginx Conf which we are using 
Server is having 60 CPU Cores with 1.5 TB of RAM
PFB part of nginx.conf of server with issue : 

worker_processes auto; 
events { 
worker_connections 4096; 
use epoll; 
multi_accept on; 
} 
worker_rlimit_nofile 100001; 

http { 
include mime.types; 
default_type video/mp4; 
proxy_buffering on; 
proxy_buffer_size 4096k; 
proxy_buffers 5 4096k; 
sendfile on; 
keepalive_timeout 30; 
keepalive_requests 60000; 
send_timeout 10; 
tcp_nodelay on; 
tcp_nopush on; 
reset_timedout_connection on; 
gzip off; 
server_tokens off; 

Regards,
Anish

Posted at Nginx Forum: https://forum.nginx.org/read.php?2,269874,270077#msg-270077