Launching Excel in a production web server on a Mac

[Jonathan Matthews]

To say that you've not given us sufficient information to help you
debug your problem would perhaps be biggest understatement I've yet
seen in 2014.

Seriously, chap - "I can't open my spreadsheet in nginx" ... are you
/really/ expecting anyone to be able to help from that minimal (if not
totally nonsensical) problem description?

Read this. End to end. And then try again:
http://www.catb.org/~esr/faqs/smart-questions.html